diff --git a/setup.py b/setup.py
index 398ba7c..ced8d42 100644
--- a/setup.py
+++ b/setup.py
@@ -200,6 +200,7 @@ setup(
     author=__about__["__author__"],
     author_email=__about__["__email__"],
 
+    python_requires=">=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*",
     install_requires=[
         CFFI_DEPENDENCY,
         SIX_DEPENDENCY,